Application of nano-diamond sensor in the field of cells

Abstract Impurities in diamonds not only have color, but also make diamonds an accurate sensor in the field of magnetic fields and temperature through impurities. When the impurity encounters a nitrogen atom, the crystal structure of the diamond changes, and a so-called nitrogen-vacancy center is formed. Nitrogen-vacancy center...
Impurities in diamonds are not only colored, but diamonds can be used as precise sensors in the field of magnetic fields and temperatures. When the impurity encounters a nitrogen atom, the crystal structure of the diamond changes, and a so-called nitrogen-vacancy center is formed. The electrons and quantum spin states in the center of the nitrogen-vacancy show striking consistency, and the quantum spin states can be precisely controlled. If the continuity of electrons in the nano-diamond can be maintained for a long enough time, we can not only realize diamond as one of the spin carrier materials of quantum computers, but diamond will also become the perfect device to reveal the secret information of nerve cells.

The nitrogen-vacancy center of the bulk diamond can store photons and carry quantum files. The invention of the new technology allows the nanodiamond structure to form a ring structure quantum, called the SP1 protein, by entering the center of the nitrogen-vacancy. However, when the problem is calculated in microseconds, the spin coherence of nanodiamonds is weak. Now Cambridge University researchers have found ways to protect the rotation of nitrogen-vacancy centers in fine synthetic diamonds, and the measurement of rotational consistency is also very high resolution.

In addition to the methods developed by the University of Cambridge above, there is no other way to accurately pass diamond sensors with only a few tens of nanometers of atoms, which is the current technical challenge. But maybe we can build a sophisticated query device, once there are many such sensors, but you can't find what you need, such as extracting a vital organ of a human cell or a critical moment such as in hundreds of sub-cells. It is much easier to find in the organs.

Since the nitrogen-vacancy center fluoresces as temperature changes, nanometer therapy or very small (about two thousandths of a Kelvin) temperature changes are measured, even in very small spaces (within 200 nm) And the measurement of the time range is possible. The researchers used a scanning confocal microscope to measure the fluorescence emitted. This microscope can migrate all light except light from a single plane, because the nitrogen-vacancy centers are sensitive to magnetic fields and electrons, and the researchers used them as a DC magnetometer for operational calculations. Therefore, in essence, researchers can prove the optical detection of nuclear magnetic resonance.

We all know that the temperature environment inside the whole active metabolic cells is different. The cell activities like mitochondria and centrosome are closely related to the hotspots of local cells. Even neurons have obvious peaks of thermal profile, and their peaks. The heat is first absorbed by the cells and then released.

The problem with nanodiamonds is that once they are placed in the cell, they must remain intact. Although other methods have been used to solve the difficulty of temperature measurement, such as genetic coded thermal sensors. But if these new nanodiamonds can be attached to proteins, like the SP1 mentioned above, then nanodiamonds will be the perfect tool for observing and understanding cell secrets. (Excerpt from "Nanodiamond sensors allow for complete surveillance at the cell level". Translation: Ma Yanping)

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